diabetic neuropathy pathophysiology ppt

It can affect different types of nerves in your body, including your sensory nerves, autonomic nerves and motor nerves. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Diabetic Ketoacidosis. Tragically, this will lead to approximately 4 million people around the world losing their sight from diabetic retinopathy, the leading cause of blindness in patients aged 20 to 74 years. A large American study estimated that 47% of patients with diabetes have some peripheral neuropathy. 3. This condition may present itself in several different ways. Tushar Patil , M.D.Senior Resident, Dept of Neurology,King George’s Medical University, LucknowIndia. Looks like you’ve clipped this slide to already. Diabetes is a pandemic health care problem affecting 366 million people globally. DIABETIC NEUROPATHY The progression of the disease is known to occur in a series of stages and is linked to glycemic and blood pressure control. IVTH B-PHARMACY You can change your ad preferences anytime. 2012 Jun;11(2):124-7. Affiliated to JNTU,Hyderabad-500008. Clipping is a handy way to collect important slides you want to go back to later. Diabetes increases the risk of foot ulceration and amputation more than 23-fold and neuropathy is the major contributory factor to this increased risk. If not ASSISTANT PROFESSOR Diabetic retinopathy (DR) is one of the most common complications of diabetes mellitus (DM) causing vision impairment even at young ages. Despite its relationship to an increased risk of cardiovascular mortality and its association with multiple symptoms and impairments, the significance of DAN has not been fully appreciated. It involves somatic sensory and motor nerves, as well as autonomic nerves. You can change your ad preferences anytime. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Diabetic neuropathy is the most common metabolic peripheral neuropathy. Clipping is a handy way to collect important slides you want to go back to later. See our Privacy Policy and User Agreement for details. Diabetic neuropathy is a common complication from diabetes, in which nerves are compromised as a result of high blood sugar levels. Presented by: Mar 29, 2018 ... Pathophysiology of diabetic nephropathy Treatment with captopril is associated with 50% reduction of in risk of combined end points of death. 13GD1R0001 High blood sugar (glucose) can injure nerves throughout your body. There is no single diabetic neuropathy. Diabetic kidney disease develops in approximately 40% of patients who are diabetic and is the leading cause of CKD worldwide. We will begin with a presentation from Dr. Aaron Vinik, who will discuss the pathophysiology and diagnosis of painful diabetic peripheral neuropathy. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. 1. The classification of the diabetic neuropathies is not yet finalised and has required successive modifications in the light of accumulating knowledge. Self Foot Care Procedures Diabetic neuropathy is the name given to nerve damage caused by diabetes. Neuropathies related to diabetes can affect 60-70% of people with diabetes[1]. The most common complication of diabetes is caused by hyperglycemia which can damage nerve fibers throughout the body . Neuropathy associated with type 1 diabetes usually develops more than 10 years after the diagnosis of diabetes. In the DCCT (Diabetes Control and Complications Trial, 1995) study, the annual incidence of neuropathy was 2% per year but dropped to 0.56% with intensive treatment of Type 1 diabetics. Diabetic Neuropathy Patrick English Diabetes Consultant Derriford Hospital Outline Size and costs of the problem Pathology/pathophysiology Risk factors Presentations ... – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 3d6bbe-NWM4Z Symptoms depend on which type of diabetic neuropathy you have. It is also called diabetic kidney disease. Looks like you’ve clipped this slide to already. Diabetes is the most common cause of peripheral neuropathy in the world[2]. Neuropathy associated with type 2 diabetes may be present at the time of diagnosing diabetes. If you continue browsing the site, you agree to the use of cookies on this website. All forms of diabetes of sufficient duration are vulnerable May coincide with CIDP, v B12 deficiency, alcoholic neuropathy, endocrine neuropathies. DIABETIC NEUROPATHY:PROBLEM STATEMENT DM risen over past two decades, 30 million in 1985 to 285 million in 2010. Continued Proximal Neuropathy. The pathophysiology of diabetic neuropathy is covered in Chapter 34 of this book. Although ESRD may be the most recognizable consequence of diabetic kidney disease, the majority of patients actually die from cardiovascular diseases and infections before needing kidney replacement therapy. Diabetic symmetric distal polyneuropathy with autonomic neuropathy This is the most common diabetic neuropathy and it is characterised by a length related distal dis-tribution of sensory and motor symptoms and signs. The PowerPoint PPT presentation: "Diabetic Retinopathy: Pathophysiology, Diagnosis, Management and Treatment" is the property of its rightful owner. SANKURATHRI.MADHURI This type causes pain (usually on one side) in the thighs, hips, or buttocks. The reported prevalence … Diabetic autonomic neuropathy (DAN) is a serious and common complication of diabetes. Under the guidance of: 1. Diabetic Foot Problems in Tertiary Care Diabetic Clinic in Thailand Int J Low Extrem Wounds. There are numerous mechanisms involved in its development such as inflammation and cellular degeneration leading to endothelial and neural damage. pinterest. Neuropathy presents as painful neuropathy in 20% of patients and it independently predicts all-cause and diabetes-r… Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. This will be followed by a presentation from Dr. David Simpson, who will discuss the management of painful diabetic peripheral neuropathy. See our User Agreement and Privacy Policy. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. If you continue browsing the site, you agree to the use of cookies on this website. Reversing Painful Diabetic Neuropathy. Pathophysiology Of Diabetic Nephropathy Ppt Metformin also known as Glucophage may be used as a fertility treatment if diabetes wristbands uk insulin resistance (which can cause ovarian cysts rd diabetes educator jobs what do type 1 diabetes have to do Approximately 40 percent of people with type 2 diabetes require insulin injections. Apr 15, 2018 DTN Staff. Now customize the name of a clipboard to store your clips. Diabetic neuropathy is implicated in 50–75% of nontraumatic amputations. DIABETIC NEUROPATHY: Diabetic neuropathies are nerve disorders associated with diabetes, which affect approximately half of all diabetes patients. Diabetic neuropathy is a type of neuropathy in people either with type 1 or type 2 diabetes. CHILKUR BALAJI COLLEGE OF PHARMACY See our Privacy Policy and User Agreement for details. Nondiabetic neuropathies may be present in patients with diabetes and may be treatable by specific measures. google plus. These mechanisms are interlinked thus worsening the diabetic retinopathy outcome. In fact, the preva-lence of diabetic neuropathy ranges from 7% within 1 year of Over time, high blood glucose levels, also called blood sugar, and high levels of fats, such as triglycerides, in the blood from diabetes can damage your nerves. DIABETIC NEUROPATHY PRESENTED BY S.MADHURI FROM CHILKUR BALAJI COLLEGE OF PHARMACY,HYDERABAD,TELANGANA. Diabetic neuropathy is nerve damage that is caused by diabetes. No public clipboards found for this slide. Diabetes is now regarded as an epidemic, with the population of patients expected to rise to 380 million by 2025. Because of differences in definition of diabetic peripheral neuropathy, epidemiologic studies reviewing an absence of symptoms have shown different results, varying from 5% to as high as 60-100%. Kosachunhanun N, et al. Most people with diabetic neuropathy are unaware that they have nerve damage, until it is picked up on routine screening by their doctor. Diabetic neuropathy is the most common complication of Diabetes Mellitus (DM), affecting as many as 50% of patients with type 1 and type 2 DM. Diabetic retinopathy (DR) is the most common microvascular complication in diabetic patients and the leading global cause of vision loss in working middle-aged adults [1, 2]. Pathophysiology of diabetic neuropathy. Gérard Said, in Handbook of Clinical Neurology, 2013. If you continue browsing the site, you agree to the use of cookies on this website. 2. Now customize the name of a clipboard to store your clips. Nerves carry messages between the brain and every part of our bodies, making it possible to see, hear, feel and move. Additional causes in 10% to 55% of patients with DM. Symptoms include the following: Diabetic neuropathy most often damages nerves in your legs and feet.Depending on the affected nerves, symptoms of diabetic neuropathy can range from pain and numbness in your legs and feet to problems with your digestive system, urinary tract, blood vessels and heart. Diabetic neuropathy is a type of nerve damage that can occur if you have diabetes. Some people have mild symptoms. Diabetic neuropathy is a diagnosis of exclusion. Motor nerves carry signals to help you move. Up to 50% of diabetic peripheral neuropathies may be asymptomatic. You have 3 types of nerves: Sensory nerves carry signals about touch, taste, sight, hearing and smell. Diabetic Neuropathy Pathophysiology Ppt Diabetes . Diabetic neuropathy is a type of nerve damage that can occur if you have diabetes. Pathophysiology Of Diabetic Nephropathy Ppt . Some of the symptoms may include tingling, burning and loss of sensation in your hands or feet. hyperglycaemic neuropathy.The symptoms,and slowing of nerve conduction,are rapidly reversed by improving glucose control. The main risk factor for diabetic neuropathy is hyperglycemia. 58 Diabetic peripheral neuropathy (DPN) is the most common complication with a lifetime prevalence of 50% with diabetes. If you continue browsing the site, you agree to the use of cookies on this website. Diabetic Neuropathy Pathophysiology Ppt . Do you have PowerPoint slides to share? A number of treatment options exist for symptomatic diabetic neuropathy. IDF projects 438 million in 2030. The best way to prevent or delay diabetic nephropathy is by maintaining a healthy lifestyle and treatin… 1. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. High blood sugar can injure nerve fibres throughout your body, but diabetic neuropathy most often damages nerves in your legs and feet. Bangabandhu Sheikh Mujib Medical University, Stanley Medical College, Department of Medicine, No public clipboards found for this slide. In type 1 DM, distal polyneuropathy typically becomes symptomatic after many years of chronic prolonged hyperglycemia, whereas in type 2, it may be apparent after only a few years of known poor glycemic control or even at diagnosis. See our User Agreement and Privacy Policy. KEY WORDS: Diabetic neuropathy, Novel treatment, Pathogenesis INTRODUCTION Peripheral neuropathy is the most common and intractable complication of diabetes1,2. About 25% of people with diabetes eventually develop kidney disease.Diabetic nephropathy affects your kidneys' ability to do their usual work of removing waste products and extra fluid from your body. If so, share your PPT presentation slides online with PowerShow.com. It can also lead to weakness in the legs. twitter. Diabetic nephropathy (DN) or diabetic kidney disease refers to the deterioration of kidney function seen in chronic type 1 and type 2 diabetes mellitus patients. Diabetic foot complications (skin changes, ulceration, infection, gangrene) are common and are attributable to vascular disease, neuropathy, and relative immunosuppression. K.ASHOK BABU Diabetic neuropathy is a common serious complication of diabetes. DIABETICNEUROPATHYDr. Diabetic nephropathy is a serious kidney-related complication of type 1 diabetes and type 2 diabetes. A wide variety of syndromes involving the peripheral nerves may be encountered in patients with diabetes mellitus, implying a correspondingly diverse range of underlying causative mechanisms. Type 2 diabetic neuropathy is frequently complicated with neuropathic pain, suggesting the involvement of small-diameter thermonociceptive nerves ().Two approaches have been developed for the diagnosis of small-fiber sensory neuropathy: psychophysical assessments by measuring thermal thresholds on quantitative sensory testing (2,3) and pathological evaluations by quantifying intra … Pathophysiology Of Diabetic Nephropathy Ppt Diabetes . Definition Epidemiology Fate of diabetes Pathophysiology Etiopathogenesis Clinical features Stage of ulcer development Classification/grading of ulcer Evaluation of a patient Management Neuropathic joint- Charcot joint Patient Education Prevention/Treatment of metatarsal head ulcer Diabetic … Worsening the diabetic neuropathies are nerve disorders associated with type 1 diabetes usually develops more than and! The light of accumulating knowledge which nerves are compromised as a result of high blood can... 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Which affect approximately half of all diabetes patients million in 2010 hyperglycaemic symptoms! Damage nerve fibers throughout the body if you have 3 types of nerves in your body, diabetic... Relevant advertising half of all diabetes patients data to personalize ads and to provide you with advertising! And User Agreement for details is the most common and intractable complication of diabetes1,2 a presentation from Aaron! Which nerves are compromised as a result of high blood sugar ( glucose ) injure.

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